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A member asked:

Can you explain if it's safe to mix nyquil (acetaminophen 325 mg- dmx 15 mg and doxylamine 6.25 mg) with 3 benedryls (25 mg)?

A doctor has provided 1 answer
Dr. Nathaniel Drourr answered

Specializes in Pain Management

Wouldn't suggest it.: Nyquil is a very sedating medication. Benadryl (diphenhydramine) is also quite sedating - especially taking 75mg's. The two together in my opinion will be too sedating and possibly dangerous.

Answered 2/20/2016

4.3k views

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