LES relaxation: Calcium channel blockers such as amlodipine can cause muscles to relax. One of these might be lower esophageal sphincter which tightens to keep stomach acid in stomach. If it relaxes inappropriately, you might notice gerd or acid reflux. Beta blockers tend to slow heart rate by negating effect of adrenaline on your heart. But beta blockers can also relax your les. Only way to find out is to try...
Answered 7/2/2018
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