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A 31-year-old member asked:

Are there any relation between skin inflammatory conditions & skin cancer ?

2 doctor answers2 doctors weighed in
Dr. Gurmukh Singh
Pathology 50 years experience
Yes: Any site with long standing inflammation can accumulate deleterious changes that may lead to cancer. Skin oner the site of chronic osteomyelitis is know to develop squamous cell cancer.
Dr. Michael Fisher
Dermatology 33 years experience
Inflammation/Cancer: For investigative cutaneous biologists a link between inflammation and skin cancer is a topic frequently discussed when multi-stage chemical carcinogenesis and photocarcinogenesis models are presented. Indeed, the inflammatory process includes the release of cytokines, growth factors, chemotactic polypeptides, and prostaglandins, which have become favorite targets for prevention of chemical induce.

Similar questions

A 31-year-old member asked:

Any relation between chronic skin inflammatory conditions & skin cancer ?

3 doctor answers5 doctors weighed in
Dr. Ally-Khan Somani
Dermatology 20 years experience
Can increase risk: Chronic inflammatory skin conditions such as those from autoimmune conditions tend to increase the risk of non melanoma skin cancers. Particularly squamous cell carcinoma. This risk is usually due to changes in the immune system together with immunosuppression from drugs being used to treat the disease. Also patients who have had lots of phototherapy are at an increased risk.

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Last updated Jul 23, 2013
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