A 31-year-old member asked:
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are there any relation between skin inflammatory conditions & skin cancer ?

2 doctor answers
Dr. Gurmukh Singh
49 years experience Pathology
Yes: Any site with long standing inflammation can accumulate deleterious changes that may lead to cancer. Skin oner the site of chronic osteomyelitis is know to develop squamous cell cancer.
Answered on Apr 13, 2012
Dr. Michael Fisher
32 years experience Dermatology
Inflammation/Cancer: For investigative cutaneous biologists a link between inflammation and skin cancer is a topic frequently discussed when multi-stage chemical carcinogenesis and photocarcinogenesis models are presented. Indeed, the inflammatory process includes the release of cytokines, growth factors, chemotactic polypeptides, and prostaglandins, which have become favorite targets for prevention of chemical induce.
Answered on Apr 14, 2012
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Yes, remote: Skin overlying an area of long standing chronic osteomyelitis may develop squamous cell carcinoma.
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