Any tips for dealing with fatigue while working at a computer late at night?

Breaks...: Sometimes an all-nighter is necessary (we've all been there), so here are a couple things that will help you make it through: breaks every 30 minutes for stretching and looking at something other than the screen. Work in a well lit room (not like the picture). Healthy snacks - peanut butter, nuts, raisins, etc. Lubricated sterile tears for the eyes. Good luck!