A member asked:

Diphenhydramine overdose antidote?

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911: Although death by Diphenhydramine overdose is uncommon, dangers associated with an overdose include cardiac arrhythmias, delirium, respiratory suppression, short-term memory loss, and urinary retention. The specific antidote for Diphenhydramine poisoning is physostigmine, usually given intravenously in a hospital. If you suspect Diphenhydramine overdose, contact emergency services (911).

Answered 12/26/2017

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Need Emergency: Medical Care. Treatment for Diphenhydramine O/D may include: administration of activated charcoal, intravenous fluids, intubation, Sodium Bicarbonate (Cardiac), Physostigmine, & benzodiazpines or barbituates for seizures. REF: https://overdoseinfo.com/diphenhydramine-overdose/

Answered 1/22/2018

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