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A member asked:
Can you tell me the relationship between insulin resistence and hepatic glucose output?
A doctor has provided 1 answer
Complex: Hi. The relationship between Insulin resistance (IR) and hepatic glucose output (HGO) is complex, an results from IR at the liver (so that Insulin doesn't suppress HGO like it should) as well as unregulated hyper-secretion of glucagon (which inappropriately stimulates HGO even in the face of high blood sugar). The liver's a little storage tank for glucose and a factory for making more!
Answered 6/25/2014
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