A member asked:

Took 1 motrin 800 3 hours ago, is it safe to take 1-2 tablets of excedrin migraine?

2 doctors weighed in across 2 answers
Dr. Paul Grin answered

Specializes in Pain Management

Not a good combo: Too many drug interactions. Ask your treating doctor for a different migraine abortive (ex. Imitrex). Hope it helps.

Answered 11/16/2016

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Yes, but...: I wouldn't do that. You've taken a large dose of ibuprofen, and you should not take any more for 8 hrs from the last dose. Now, the drug you've mentioned has a small amount of aspirin, of generic tylenol, (acetaminophen) and of caffeine. Doubt it enhance your major dose of ibuprofen. You can repeat the Motrin at 8 hrs, but if your headache is that severe you should seek some guidance from your doctor. Good luck.

Answered 9/26/2020

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