A member asked:

What is considered treatment resistant depression?

6 doctors weighed in across 2 answers

A formidable emotion: Trd is a type of depression that fails to respond to standard clinical treatments (psychotherapy, medication) over a prescribed period of time. Trd symptoms can range from mild to severe and during the course of care may require combination treatments and ancillary services, such as functional/environmental analysis, activity scheduling, and behavioral planning, .

Answered 10/4/2016

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Dr. James Fox answered

Failure of one med: Treatment-resistant depression (TRD) typically refers to inadequate response to at least one antidepressant trial of adequate doses and duration. TRD is a relatively common occurrence in clinical practice, with up to 50% to 60% of the patients not achieving adequate response following antidepressant treatment.

Answered 11/10/2015

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