Is it true tylenol (acetaminophen) can reduce fear and.anxiety in the brain?

Not likely.: Acetaminophen (which is the same thing as panadol and tylenol (acetaminophen) and paracetamol) does not have an anti-anxiety effect. However, it probably does have a placebo effect (which is legitimate) - if you think it helps your anxiety, it will. But there are far healthier ways to reduce fear and anxiety than biologically unhelpful medications.