A member asked:

My wife ( pcos ) , is on her 7 th cycle with clomid (clomiphene) 200 mg bd + letroz 2.5 mg bd; possibility of birth defects ? iui on tomrrw. quick ans. pls!

6 doctors weighed in across 2 answers

No: If taken appropriately Clomid (clomiphene) and Letrozole will not increase the risk of a birth defect.

Answered 9/28/2016

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Dr. John Holden answered

Specializes in Fertility Medicine

7 clomid (clomiphene) cycles: Birth defects are not a concern in pregnancies conceived while taking either Clomid (clomiphene) or letrazole. However, if your wife is not pregnant after 6 cycles on clomid, (clomiphene) it is time to move on to a more agressive modality!

Answered 11/27/2017

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