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A member asked:
What induces apoptosis in cancer cells?
8 doctors weighed in across 2 answers
Many factors.: There are many factors/regulators that induce apoptosis in cancer and normal cells. These are defective or turned off in cancer cells. For example, the x-linked inhibitor of apoptosis protein (xiap) is overexpressed in cancer cells. Xiaps bind to caspase-9, and suppress apoptotic activator cytochrom c, allowing the damaged cells to live. Deactivation of p53 apoptotic protein is another example.
Answered 9/1/2012
5.9k views
Chemotherapy: All chemotherapy or treatment eventually leads to apoptosis or cell death.
Answered 8/11/2012
5.9k views
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