A member asked:

Do the kidneys or does the liver make platelets?

3 doctors weighed in across 2 answers

Neither: The liver produces thrombopoietin which is responsible for stimulating the marrow to make platelets. Some folks make platelets in the lungs, and babies may make some in the liver and spleen.

Answered 10/23/2018

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Neither...: The bone marrow makes platelets. They are produced by the fragmentation of megakaryocytes, which are very large, polyploid bone marrow cells produced by the process of endomitosis. Lots of things influence platelet production and utilization (but that's for another healthtap question).

Answered 2/4/2014

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