A member asked:

Mammogram with punctate pleomorphic calcifications. is that breast cancer?

22 doctors weighed in across 4 answers

Oxymoron: Microcalcifications are usually described as either punctate (benign) or pleomorphic (in determinant to suspicious) not both. Ultimate definitive diagnosis may require tissue sampling that is best done via stereotactic guided core biopsy. See a breast surgeon for further evaluation.

Answered 12/19/2014

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Depends, not likely.: Usually, calcifications do not mean cancer, and are not themselves cancerous. However, tight clusters of microcalcifications are seen with breast cancer. Many times, a repeat mammogram would be done in about 6 months to see if there are changes. If there were, a biopsy would be done. At this point, it would appear that no suspect changes are noted. Check with your doctor to be sure.

Answered 4/11/2012

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Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy.

Answered 9/11/2019

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Dr. Michael Gabor answered

Specializes in Diagnostic Radiology

You can't : be sure it's cancer until it's biopsied. "Punctate" and "pleomorphic" are mutually exclusive terms, so the description of the microcalcifications doesn't make sense. It's like calling something square and round at the same time....it is impossible. Moreover, punctate usually implies benignity, and pleomorphic is suspicious. Were they called suspicious? Was a biopsy recommended?

Answered 7/16/2014

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