A member asked:

My anti ccp is 300 , am taking 17.5 mg mtx and will start soon a combination of enbrel (etanercept) and mtx is that good ?

3 doctors weighed in across 2 answers

Very good: For patients with RA who cannot achieve a remission on Methotrexate alone, the addition of a biologic such as Enbrel (etanercept) is the next step.

Answered 6/28/2014

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Combination therapy: Rheumatoid arthritis should be diagnosed and managed by a trained rheumatologist. The anti-ccp antibody is highly specific for RA. Methotrexate, in combination with other medications, can often successfully treat RA and prevent joint damage. Sometimes, MTX is combined with sulfasalazine and hydroxychloroquine. Alternatively, a "biologic" agent is added such as Etanercept (Enbrel), which blocks TNF

Answered 3/18/2015

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