depression.emedtv. COM: In clinical studies on cymbalta (duloxetine), (duloxetine) weight gain was reported by at least 1 percent of people taking the medication. However, it is more typical for people to lose weight while taking cymbalta (duloxetine). If you do notice weight gain during treatment, talk to your healthcare provider. He or she may recommend lifestyle changes, such as eating heart-healthy foods and exercising more, or may suggest switching to another antidepressant.
Answered 4/9/2016
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