A member asked:

What is the difference: hydrocodone vs. codeine?

A doctor has provided 1 answer

One semi-synthetic: Codeine is a naturally occurring chemical found in opium, along with morphine and papaverine. The problem is that Codeine is poorly absorbed (like morphine) and higher doses are needed for it to work, in addition it has histamine effects like sneezing, itching and GI distress. Hydrocodone adds a molecule to codeine, where it is better absorbed and more potent, with fewer histamine side effects.

Answered 6/24/2014

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