A 33-year-old member asked:
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the decision was that i have lobular carcinoma in situ. what is it?

1 doctor answer
Dr. Andrew Turrisi
46 years experience Radiation Oncology
Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer.
Answered on Nov 24, 2012
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1 comment
Dr. Richard Orr
Dr. Richard Orr commented
43 years experience Surgical Oncology
Mirror image biopsies were done many years ago, but are rarely indicated today. Most of us feel that bilateral mastectomy is overkill, but some patients opt for it, especially if they have a family risk in addition to LCIS. We frequently consider tamoxifen (an anti-estrogen) as a risk modifier, as it decreases the risk of development of invasive cancer by 50%. Women with LCIS are at risk of developing invasive ductal as well as invasive lobular cancer, and may develop it in either breast and in any site, which is why mirror image biopsies are not helpful.
Nov 24, 2012

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