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A member asked:
Could hydrocodone affect serotonin in any way?
A doctor has provided 1 answer
Depression: Long term use of opioids, such as hydrocodone, can cause depression. Low serotonin levels also cause depression. If you have a history of depression and are not being treated, use of hydrocodone can make the depression worse. Theoretically, this could be due to low serotonin levels.
Answered 1/15/2014
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