A 36-year-old member asked:
Could hydrocodone affect serotonin in any way?
1 doctor answer • 1 doctor weighed in
Anesthesiology 24 years experience
Depression: Long term use of opioids, such as hydrocodone, can cause depression. Low serotonin levels also cause depression. If you have a history of depression and are not being treated, use of hydrocodone can make the depression worse. Theoretically, this could be due to low serotonin levels.
4.6k viewsAnswered >2 years ago
Last updated Jan 15, 2014
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