Can monobactams work to treat pseudomonas aeruginosa?

Maybe: Monobactams are drugs chemically similar to the penicillins. The only commercially available monobactam in the United States is a drug called aztreonam, it is effective against some strains of pseudomonas but not all. Because of this it is more of a second choice agent in those who can not take drugs that have greater efficacy because of allergies etc.

Yes: But this depends upon what infection and the sensitivities of the strain of pseudomonas with which the patient is infected.

Aztreonam: Is the only monobactam available in the usa. It does have activity against pseudomonas but hospital strains may be resistant.