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A member asked:
I'm curious as to what effect would lidocaine have on action potential generation and conduction?
A doctor has provided 1 answer
Na channel blocker: By inhibiting Na channels Lidocaine affects action potential phase 0 ( class 1B antiarrhythmic). It can cause dose-dependent depression, reduction in action potential duration and failure of propagation/ conduction
Answered 8/6/2014
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