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A member asked:

Help docs! i'm trying to find out what causes large platelets and hypersegmented neutrophils?

A doctor has provided 1 answer

Maybe two things?: Platelets that are a little bit above or below reference range size seldom mean anything if the platelet count itself is normal and there's nothing to suggest compensated autoimmunity. Hypersegmented neutrophils suggest B12 or Folic Acid deficiency from some cause as the first possible problem worth checking.

Answered 6/25/2014

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