What is my risk of having another baby with spina bifida?

Complex question: This question is difficult to answer without additional information such as the type of spina bifida you baby has, the presence of any other abnormalities and a complete family history. Most cases of isolated spina bifida are sporadic and are not strictly inherited. For a more precise answer, you can seek a genetic evaluation (geneticist/genetic counselor).

If simple SB, 4%: Of interest any pregnancy has about a 4% risk of unexpected event, adding together sporadic issues like cleft lip or palate, infection, etc. While sb is not a straightforward genetic event, previous neural tube defect increases your risk of another to ~4% while 2 prior would increase risk to~10%. A thorough evaluation of your family tree with a geneticist can add up all the factors for any risks.