How long time after taking last ibuprofen can i drink alcohol normally?

2-4hours half-life: Ibuprofen has a relatively short half-life (the time it takes for 1/2 to disappear in your body) is only about 2-4 hours. Typically, after 5-6 half-lives, there isn't much left in the body following the last dose. If you are not using it regularly, then it is less of a concern. Say u took 800mg dosage, 8-10 hrs later, maybe.