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A 41-year-old member asked:

Do genetics play a big role in krabbe disease?

1 doctor answer2 doctors weighed in
Dr. Maulik Shah
Clinical Genetics 25 years experience
Yes: Krabbe is a genetic inherited condition. It is inherited in an autosomal recessive fashion. That means that for a patient with krabbe, both parents are usually carriers of the abnormal gene called galc. Those parents will have a 25% chance of having another affected child and a 50% chance of having children that are carriers.
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Last updated Apr 12, 2014
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