Can bacterial infection cause gallbladder disease?

Other way around.: Gallbladder disease is almost always secondary to gallstones blocking the cystic duct that empties the gallbladder. Persistent blockage leads to acute inflammation of the gallbladder called acute cholecystitis. Studies have shown that the bile is secondarily infected with bacteria approximately 15% of the time.

Gallstones: Gallstones are formed in the gallbladder and may not cause symptoms . Gallstones in the gallbladder are associated with bacteria in the bile and if the bile in the gallbladder gets infected it causes cholecystitis which makes you very unwell and requires surgery to remove the gallbladder.