A member asked:

Can 'vaping' (e-cigerettes) with nicotine in a propylene glycol solution cause elevated liver enzymes. not sure if nicotine has an effect on liver? ty

3 doctors weighed in across 2 answers

No: Nicotine has no adverse effect upon the liver unless you had a major overdose which only happens with the administration of large doses of nicotine. These doses cannot be met by smoking or vaping. Propylene glycol won't cause problems either. I would worry about chronic lung damage and nicotine addiction. If your liver enzymes are elevated, your doctor needs to find out the reason.

Answered 11/25/2013

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Vaping: "Smoking may affect the liver through inflammatory pathways and may aggravate the pathogenic effects of alcohol on the liver. " REF: https://www.ncbi.nlm.nih.gov/pubmed/20511375.As of 11 SEP 2019 The Centers for Disease Control and Prevention reported 6 deaths & > 450 possible cases of severe lung injury in 33 states & 1 jurisdiction related to vaping. Mechanism of injury is poorly understood.

Answered 9/16/2019

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