My daughter is 45 years old, and her period is two weeks late. how likely is it that she could be pregnant?

Easy to find out: Just do a home preg test, which would be + if she was, at her age 45 it is more likely that she is peri-menopausal and starting to naturally skip periods, but a home pt will let her know.

Pregnant: It is not likely that she is pregnant. Purchase a pregnancy test to get a definitive answer. More than likely, she is approaching menopause.