Hyperpolarization: Highly elevated ionized calcium can lead to a variety of symptoms, including dehydration, polyuria/polydipsia, confusion, constipation and sometimes pancreatitis. Asthenia and weakness are common and can progress to a flaccid paralysis. Cardiovascular effects include shortened qt, av block, and brady or tachydysrhythmias. Muscular effects are related to hyperpolarization caused by high calcium.
Answered 10/24/2017
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