No clinic symptoms. ena results all 0.2. rnp/sm rised from 1.0 to 1.6 in 3yrs. doctors say no big deal. what if it continues to rise as in these 3yrs?

symptoms are key: If you don't have any symptoms but have slightly elevated antibodies to rnp and ENA (ribonucleoprotein and extractable nuclear antigen) there isn't any need for treatment. Diagnosis of mixed connective tissue disease, lupus, and similar conditions does require a thorough history and exam - best done by a rheumatologist.

Then may be: That will need clinical correlation and appropriate intervention.