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MK
A 41-year-old female asked:

No clinic symptoms. ena results all 0.2. rnp/sm rised from 1.0 to 1.6 in 3yrs. doctors say no big deal. what if it continues to rise as in these 3yrs?

2 doctor answers3 doctors weighed in
Dr. Geoffrey Rutledge
Internal Medicine 39 years experience
symptoms are key: If you don't have any symptoms but have slightly elevated antibodies to rnp and ENA (ribonucleoprotein and extractable nuclear antigen) there isn't any need for treatment. Diagnosis of mixed connective tissue disease, lupus, and similar conditions does require a thorough history and exam - best done by a rheumatologist.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ajay Acharya
A Verified Doctoranswered
39 years experience
Then may be: That will need clinical correlation and appropriate intervention.
Created for people with ongoing healthcare needs but benefits everyone.

Similar questions

MK
A 41-year-old female asked:

No clinic symptoms.Ena results all 0.2. Rnp/sm rising from1.0 to 1.6 in 3yrs.Doctors say no big deal? What if it continues to rise as in these 3yrs?

1 doctor answer1 doctor weighed in
Dr. Kenneth Smith
Internal Medicine 34 years experience
No clinical sx: If no clinical symptoms criteria for disease not met. ANA can be very reliable in diagnosis with symptoms consistent with disease state. But false positive results occur. The question should be why was test run.
Created for people with ongoing healthcare needs but benefits everyone.
MK
A 41-year-old female asked:

No clinic symptoms.Ena results all 0.2. Rnp/sm rising from1.0 to 1.6 in 3yrs.I'm afraid of progress. Doctors say no big deal, but why raising than?

1 doctor answer2 doctors weighed in
Dr. Ed Friedlander
Pathology 46 years experience
Stop worrying: I am going to assume that your rnp/smith are below the ranges that the lab considers significant. All immunoassays turn up some positivity because the of cross-reactivity of other antibodies that you may develop from meeting different micro-organisms or goodness-knows-how. The miniscule rise in activity means nothing, your physicians were right to say thing ; if you had mctd you'd know u r sick.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 1, 2015

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