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A 72-year-old male asked:

is there any significance to the sequence in which i take eye drops for glaucoma? i use cospot, alphagan-p and xalatan (latanoprost). thanks.

4 doctor answers5 doctors weighed in
Dr. Olivia Liao
Ophthalmology 31 years experience
Any order is fine: Just wait about three minutes between simultaneous drops keeping eyes gently closed and pressing on the inside corner of the eye to the nose bone.
Dr. Aziz Khanifar
Ophthalmology 19 years experience
No: The order does not matter. If all drops are to be taken at the same time of day, make nature you wait a little between drops to ensure they don't rinse each other out.
Dr. Jon Fishburn
Ophthalmology 30 years experience
Yes: Your treating md will advise you, but a common practice is to use your cosopt™ and alphagan™ twice per day. You should wait at least 5' between eye drop instillation and also apply pressure to the inner corner of your eyelid for one minute. A twice/day regimen is ideally 12 hrs apart. Also, it does not matter the order. Xalatan™ is instilled generally close to bedtime by the same technique.
Dr. Charles Turck
Pharmacology 17 years experience
No: There is no best order in which to administer these three eye drops. It is important to wait at least 5 minutes between each medication and it is best practice to close your eye and press on the inner corner of the eye for 1 minute after administration to ensure the medication is absorbed.

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Last updated Apr 10, 2020
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