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A 27-year-old male asked:

I currently take on the morning 100mg quetiapine, 36mg concerta, 300mg wellbutrin (bupropion) xl. does the quetiapine affect the concerta? i also take 200mg quetiapine and 4mg klonipin at night.

2 doctor answers • 3 doctors weighed in
Dr. Bachar Al-Alami
Dr. Bachar Al-Alamianswered
ADHD & Autism 38 years experience
YES Need Monitor : No problem with welbutrin . Concerta and quetiapine yes monitor : data demonstrate that the specified agents may interact with each other in a clinically significant manner. The benefits of concomitant use of these two medications usually outweigh the risks. An appropriate monitoring plan should be implemented to identify potential negative effects. Dosage adjustments of one or both agents may be.
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1 comment
Dr. Donald Jacobson
A Verified Doctor commented
A US doctor answered Learn more
I would question the need for quetiapine during the day. If you were to take it at night you may get by on less Klonopin. I have a number of patients on this combo and have not encountered problems with it: usually BPD type 2. , ADD , and anxiety
Oct 8, 2013
Dr. Michael Arena
A Verified Doctoranswered
24 years experience
It can.: The combination of wellbutrin (bupropion) and Concerta (though sometimes used together) may increase your risk of having a seizure. You should speak to your prescriber about this.
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