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A 37-year-old member asked:

will benadryl (diphenhydramine) temporarily suppress a human bite? dont want anyone to know

1 doctor answer2 doctors weighed in
Dr. Thomas Namey
Rheumatology 48 years experience
Not really.: A human bite is dangerous if skin was broken and almost always needs antibiotics (generci Augmentin rx of choice). If skin was not penetrated, i cannot understand how taking Benadryl (diphenhydramine) can help.

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CA
A 38-year-old member asked:

What is the difference between first and second-generation antihistamines?

3 doctor answers5 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
Side effects: The second generation antihistamines were developed to try and decrease the side effects of the first generations. Many are "purified" first generation antihistamines so they have the active effects without the side effects of drowsiness, sedation, dry mouth etc. They also tend to have longer half lives, meaning they can be taken once or twice a day not every 4 hours.
CA
A 39-year-old member asked:

Are there any prescription antihistamines?

2 doctor answers12 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
A few: Antihistamines have been around for many years & many that used to be prescription are now available over-the-counter. A few antihistamines are still prescription, including some first-generation (sedating) medicines like periactin or palgic as well as second-generation (less-sedating) medicines like xyzal (levocetirizine) and clarinex.
Dr. Maziar Rezvani
Allergy and Immunology 21 years experience
Hydroxyzine is still prescription as well
Nov 23, 2011
Dr. Paul Carter
A Verified Doctor commented
A US doctor answered Learn more
Many prescription medications have antihistamine properties. Talk to your personal physician about which medications are right for you.
Jan 1, 2012
A 27-year-old member asked:

Why is it that Benadryl (diphenhydramine) gives me a hangover?

2 doctor answers4 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
Crosses into brain: There is a blood:brain barrier and medications can cross through this barrier to cause people to feel "hungover". People complain of feeling drowsy or paradoxically some people get insomnia. Non-sedating antihistamines (fexofenadine, loratidine, cetirizine) have less of this "crossover" and so cause less problems for people.
CA
A 38-year-old member asked:

Can you take Benadryl (diphenhydramine) while taking orlistat?

2 doctor answers3 doctors weighed in
Dr. Pedro Hernandez
Geriatrics 40 years experience
Yes: No incompatibility on my computer program. Always check with pharmacists.
A 48-year-old member asked:

Why do I get short of breath after taking a benadryl (diphenhydramine)?

2 doctor answers5 doctors weighed in
Dr. Garrett Caldwell
Dr. Garrett Caldwellanswered
Family Medicine 9 years experience
Benadryl (diphenhydramine): Benadryl (diphenhydramine) is a sedating drug. This could cause some respiratory depression that is making you sob. However, you may also be allergic to the drug. If you believe you are allergic, you should avoid the drug and speak to your physician. An allergy can cause you to stop breathing after taking it.
Dr. Matthew Davis
Child Psychiatry 19 years experience
This is an unusual complaint from Benadryl. If the symptoms are severe it may, in fact, be an allergy. However, allergies to Benadryl are rare and it is generally very effective in treating allergies. An allergy to Benadryl is more likely from any dyes used in the tablet or capsule and a dye-free form of the medication should be used instead if this is the case. Shortness of breath may be part of any paradoxical symptoms when using the medicine too early in the day when the "need for sleep" is not yet present and the sedating effects conflict with the drives to stay awake. This could lead to a rapid pulse and hyperventilation. Try to limit any daytime use of Benadryl except for bad allergies that would otherwise prevent daytime functioning. If you need to take Benadryl for several days, take it at night to allow the sedation to work in your favor. If nighttime use at appropriate doses doesn't help, then you may want to opt for a "non-sedating" antihistamine, although of those, Zyrtec can still be sedating and Claritin may not be effective. Allegra appears to be more uniformly non-sedating while still effective for most people. (Note: the generic formulations of these medications are just as effective. I refer to brand names because they are better known to most.)
Jan 4, 2013

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