How/where is the brain affected by copper accumulation?

Copper: Excess copper in the body is released in the blood and can accumulate in the tissues, particularly in the kidneys, eyes, and brain. When it goes to the brain, it usually deposits in nerves that are associated with movement, perception, and mood regulation. This causes a patient to lose coordination and become clumsy. Seizures, migraines, and cognitive defects may also result from excess copper.

Only limited info: We know that wilson's disease is an issue with copper (and ceruloplasm), and can cause a slowly progressive type of dementia(perhaps due to live involvement), we know that copper deficiency can cause a peripheral neuropathy similar to pernicious anemia, and may also cause encephalopathy, there is some literature that varying copper levels may have an indirect role in alzheimer's disease.