A 40-year-old member asked:
How long does benadryl (diphenhydramine) keep you drowsy?
1 doctor answer • 1 doctor weighed in
Dr. Joseph O'Bryananswered
Family Medicine 29 years experience
Benadryl (diphenhydramine): Most people it will last 8 hours or so but I have seen people who still feel groggy 12 hours later or more
Created for people with ongoing healthcare needs but benefits everyone.
3.9k viewsAnswered >2 years ago
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A 37-year-old member asked:
How long does it take for Benadryl (diphenhydramine) to make you drowsy?
1 doctor answer • 2 doctors weighed in
Dr. Tammi Schlichtemeieranswered
Pediatrics 33 years experience
About 45 minutes: Benadryl (diphenhydramine) can make some people drowsy. The maximum effect occurs in about 45 minutes or so. However, it can result in hyperalertness in some people.
Created for people with ongoing healthcare needs but benefits everyone.
5.7k viewsReviewed >2 years ago
A 29-year-old member asked:
How long does drowsiness generally last after a benadryl (diphenhydramine)?
1 doctor answer • 1 doctor weighed in
Dr. Anthony Rooklinanswered
Allergy and Immunology 51 years experience
Four to six hours: The half life of Benadryl (diphenhydramine) is about four to six hours and usually the sedation will wear off within that time frame. As one continues to use it often a certain amount of tolerance develops and less sedation is appreciated. Studies have shown that its effect on brain function still continues despite less sedation.
Created for people with ongoing healthcare needs but benefits everyone.
5.7k viewsAnswered >2 years ago
Last updated Apr 28, 2018
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