Question 1

how do thiazides reduce calcium excretion through urine? and how do loop diuretics increase the excretion of calcium through urine?

Accepted Answer

you're right: They do exactly what you said: thiazides reduce urinary calcium excretion and are good for stone formers; loop diuretics increase it and are good for people with hyperparathyroidism and hypercalcemia. The mechanism is complicated. Unless you're taking an exam, this is sufficient information.

Question 2

how come thiazides are called low ceiling diuretics?

Accepted Answer

Low ceiling: Who calls thiazides 'low ceiling' diuretics. This is a new term for me. Why not ask whoever gave you that terminology.

Question 3

which thiazide diuretics are most frequently prescribed?

Accepted Answer

Two below: The most frequently used thiazide diuretics are:
HCTZ (hydrochlorothiazide).
Chlorthalidone

Question 4

why are thiazide diuretics used in diabetes insipidus?

Accepted Answer

Paradox: Thiazides paradoxically reduce the amount of urine the kidneys produce in the nephrogenic form of di. Thiazides are not used in the central form.

Question 5

why thiazides diuretics contraindication with impaired renal failure ?

Accepted Answer

Renal filtration : The renal tubules are effected adversely with thiazides , preventing distal resorption of sodium and water , thus aggravating the renal clearance of BUN , cr, and other toxins in the blood.

Question 6

resubmit #: is there a thiazide diuretic medication(s) that does not raise glucose levels?

Accepted Answer

Glucose: We keep learning that more of our meds cause some elevation of glucose. I am unaware of any members of the thiazides family that don't cause this. The long term importance of this effect is not certain.

Question 7

can thiazides diuretic cause impaired renal function if it used to control bp inckd what is the safest antihypertensive drugto be used with ccb&bblock?

Accepted Answer

HTN: HCTZ can worsen renal function. 
Safer drug would be Amlodipinene 
Hydralazine , procardia

Question 8

doc added a thiazide diuretic to my bp regimen. take creatine as a workout supplement. as both like to gobble water, one to the muscles and the other (kidney?). is this a bad continued process or okay?

Accepted Answer

Creatine: Creatine is safe and doesn't lead to dehydration as any storage of water by it to muscles is quite minor and insignificant.

Question 9

which of the diuretics (thiazide, loop, potassium sparing) if you were to choose just one may be the best overall to treat hbp?

Accepted Answer

Depends: On multiple issues including kidney function. Certain diuretics work better with certain levels of kidney function/dysfunction. In general a thiazide is preferred as first line and particularly Chlorthalidone as it is long acting and potent. See your doctor for specifics as kidney function and potassium levels need to be followed.

Question 10

suggestions to discuss with my doctor: hypertension (on avapro 150 now), anxiety, and pvcs. what medication would you consider? ssri, beta blocker, thiazide diuretic, combination of any? want to start beta b, but weary of rebound tachyarrhythmias?

Accepted Answer

My thoughts : I eschew beta blockers due to adverse effects such as fatigue, exercise intolerance, syncope, asthma, cognition issues, cardiac complications, and stopped years ago. Many newer anti-BP meds (even use of cocoa). Meet with your doctor

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Doctor answers about:

Thiazide diuretics and calcium

A member asked:

How do thiazides reduce calcium excretion through urine? and how do loop diuretics increase the excretion of calcium through urine?

A member asked:

How come thiazides are called low ceiling diuretics?

A member asked:

Which thiazide diuretics are most frequently prescribed?

A member asked:

Why are thiazide diuretics used in diabetes insipidus?

A member asked:

Why thiazides diuretics contraindication with impaired renal failure ?

A member asked:

Resubmit #: is there a thiazide diuretic medication(s) that does not raise glucose levels?

A member asked:

Can thiazides diuretic cause impaired renal function if it used to control bp inckd what is the safest antihypertensive drugto be used with ccb&bblock?

A member asked:

Doc added a thiazide diuretic to my bp regimen. take creatine as a workout supplement. as both like to gobble water, one to the muscles and the other (kidney?). is this a bad continued process or okay?

A member asked:

Which of the diuretics (thiazide, loop, potassium sparing) if you were to choose just one may be the best overall to treat hbp?

A member asked:

Suggestions to discuss with my doctor: hypertension (on avapro 150 now), anxiety, and pvcs. what medication would you consider? ssri, beta blocker, thiazide diuretic, combination of any? want to start beta b, but weary of rebound tachyarrhythmias?

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