Question 1

what is the best treatment for synovial sarcoma?

Accepted Answer

It is not: A common dx, unlike its name, does not always occur at joints, but is lumped as a "soft part sarcoma" so it can metastasize to lungs, but unlike many sarcomas, it can also travel to lymph nodes. Resection free margins is key.  Even 1 node conveys higher risk of relapse. Statistics don't help. You have a chance!

Question 2

for a synovial sarcoma are imatinib or everolimusm effective?

Accepted Answer

These have no: Established role in front line therapy. Are they being offered on a clinical trial? Both are costly, and possibly of theoretic use. Ask for the strength of the data (it will be called a phase ii trial), .

Question 3

if you have synovial sarcoma how would you know ? would you feel a lump?

Accepted Answer

Maybe: Synovial sarcoma is a diagnosis made by microscopic evaluation of biopsied tissue and special stains of tissue and possibly markers done on flow cytometric studies.  You may feel an irregularity or bump, depending on the size of the questionable area.  Put your mind at ease and be seen by your doctor.

Question 4

how serious is synovial sarcoma?

Accepted Answer

Very: Synovial sarcomas are serious cancers of the joints. Surgery can be curative, and chemotherapy may also be recommended to decrease the risk for a recurrence.

The size of the tumor, and invasion of structures in and around the joint are predictive of cure or recurrence.

Question 5

what are the symptoms of synovial sarcoma?

Accepted Answer

Synovial sarcoma: Synovial sarcoma usually occurs in the joints of the legs or arms and often occurs in younger individuals. Generally this presents as a painless swelling however advanced stages can be accompanied by weight loss and fatigue.

Question 6

what are the chances of one surviving synovial sarcoma?

Accepted Answer

IIt is not: A common dx, unlike its name, does not always occur at joints, but is lumped as a "soft part sarcoma" so it can metastasize to lungs, but unlike many sarcomas, it can also travel to lymph nodes. Resection free margins is key.  Even 1 node conveys higher risk of relapse. Statistics don't help. You have a chance!

Question 7

what are the current immuno-therapies for synovial sarcoma?  how effective are them?

Accepted Answer

Experimental: Despite "pop" claim and excitement, immunotherapy has historically been a bust for sarcomas. There 's some new stuff but it'a way early. There is a melanoma-sarcoma group at Sloan Kettering; Dr. D'Angelo may have something. Good luck.

Question 8

what is the treatment for synovial sarcoma?

Accepted Answer

It is not: A common dx, unlike its name, does not always occur at joints, but is lumped as a "soft part sarcoma" so it can metastasize to lungs, but unlike many sarcomas, it can also travel to lymph nodes. Resection free margins is key.  Even 1 node conveys higher risk of relapse. Statistics don't help. You have a chance!

Question 9

are there any treatments for synovial sarcoma?

Accepted Answer

Yes: Treatment of synovial sarcoma is centered on surgical removal of the tumor with a cuff of normal tissue around it (medical term is wide resection). Radiation is given either before or after surgery in many cases. Use of chemotherapy is controversial as it gives a minimal improvement in survival rates at best.  Chances of cure are about 60-70% overall, but every case is different.

Question 10

any docs familiar with synovial sarcoma? what can you tell me about it?

Accepted Answer

Very aggressive: synovial sarcomas are aggressive malignancies of the extremities.  They arise in the synovial tissue adjacent to  joints of the extremities especially around the feet.  If allowed to grow before biopsy then when  mets are found, cure is difficult.  Early suspicion leading to biopsy and resection is the best approach in an attempt to cure.

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Synovial sarcoma lung metastasis

A member asked:

What is the best treatment for synovial sarcoma?

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For a synovial sarcoma are imatinib or everolimusm effective?

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If you have synovial sarcoma how would you know ? would you feel a lump?

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How serious is synovial sarcoma?

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What are the symptoms of synovial sarcoma?

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What are the chances of one surviving synovial sarcoma?

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What are the current immuno-therapies for synovial sarcoma? how effective are them?

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What is the treatment for synovial sarcoma?

A member asked:

Are there any treatments for synovial sarcoma?

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Any docs familiar with synovial sarcoma? what can you tell me about it?

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