Any docs familiar with synovial sarcoma? what can you tell me about it?

Very aggressive: synovial sarcomas are aggressive malignancies of the extremities. They arise in the synovial tissue adjacent to joints of the extremities especially around the feet. If allowed to grow before biopsy then when mets are found, cure is difficult. Early suspicion leading to biopsy and resection is the best approach in an attempt to cure.

Rare cancer: It is a rare cancer that usually arises close to joints in younger people. Treatment is with surgery and radiation. It is not clear if chemotherapy helps, but of all sarcoma types, synovial may be more sensitive to chemo than others. If it is caught before it spreads, it can often be cured. If it spreads, it usually goes to the lungs and sometimes the lymph nodes. Need for amputation is rare.

Sarcoma specialist: As per NCCN guidelines, patients should be diagnosed and managed at a multidisciplinary sarcoma center when possible. If tumor is localized, surgery and radiation are recommended with chemotherapy generally reserved for patients for patients with intermediate or high grade tumors larger than 5 cm. Chemotherapy is the mainstay of therapy for patients whose tumors have spread.