Question 1

what is scleroderma crest variant?

Accepted Answer

Limited : The limited cutaneous form of systemic sclerosis is also referred to as crest syndrome. "crest" is an acronym for calcinosis, raynaud's syndrome, esophageal dysmotility, sclerodactyly, and telangiectasia.

Question 2

is crest syndrome the same as scleroderma?

Accepted Answer

Crest syndrome: Different from scleroderma only by sparing the kidneys.

Question 3

is a ana + with mixed patterns 1:80 homogeneous n 1:160 centromere sufficient enough to diagnose 4 crest/scleroderma  or additional tests needed?

Accepted Answer

Auto Immune disease: You need additional testing to diagonals crest/scleroderma.  You should also see the rheumatologist to confirm the disease before you
worry that you have scleroderma or not.

Question 4

tested positive for 2nd time ana 1:160 centromere on 3/4 n 4/5. tested neg 4  sl-70. what additional test can be done to rule out crest/scleroderma?

Accepted Answer

See details: You keep asking the same question over and over again. There is no additional testing. You either have clinical symptoms consistent with the diagnosis or you do not. If you do not, then you do not have the diagnosis.

Question 5

what is the best climate for me. i have lupus scleroderma ra fibromyalgia and crest syndrome ?

Accepted Answer

The Mighty Vitamin D: You may do better in warmer climate closer tot he equator for 2 reasons: more vitamin D and more exercise . Receiving more sunlight would naturally raise your vitamin D levels. Adequate vitamin D is essential for fibromyalgia relief, and is a powerful anti-inflammatory.More exercise, especially light walking or yoga on the beach would add to the benefit of vitamin D.

Question 6

ana positive 1:80 homogeneous pattern & 1:160 centromere pattern...additional tests needed or just by centromere pattern crest & scleroderma r present?

Accepted Answer

Almost certain: Positive anti-centromere antibodies would indicate the presence of scleroderma/crest, better if anti–scl-70 antibodies also present, plus clinical symptoms and signs.

Question 7

can i have secondary pulmonary hypertension due to crest scleroderma?

Accepted Answer

Scleroderma: Yes you can develop pulmonary hypertension with crest syndrome, but it is less common than with other forms of scleroderma.

Question 8

other than crest/scleroderma what other virus/bacteria/disease can cause a positive ana with centromere pattern?

Accepted Answer

A lab error: The evaluation of these things by an inexperienced technician / pathologist is fraught with possibilities for error.

Question 9

is crest syndrome with high centromere b antibody considered a rare disorder with rheumatologists having only a few such patients?  should i seek out a scleroderma specialty center for regular care?

Accepted Answer

It's your call: I'm glad that you got your diagnosis. It's your call whether to seek a sub-subspecialist. Often your best move is to become scientifically literate and read the real journal articles having to do with your disease. The key decision in your management will probably be whether, when and how to manage any pulmonary arterial hypertension. See if you have someone locally who you like & trust.

Question 10

ana speckled pattern 1:80 with antigen detected for high sle titer,  sjordens, high titers scleroderma, crest and pbc....how worried should i be?

Accepted Answer

Need context.: We need to discuss your symptoms, what condition were you in when the blood test was taken (were you ill? Cold? Flu-like symptoms?), family history, medical conditions &amp; medications you took to properly interpret the ANA pattern. You can't base everything on the report alone, since ANA titers change with time &amp; condition. It's unlikely that you have ALL of these rare diagnoses. Use HealthTap Prime

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

Scleroderma crest variant

A member asked:

What is scleroderma crest variant?

A member asked:

Is crest syndrome the same as scleroderma?

A member asked:

Is a ana + with mixed patterns 1:80 homogeneous n 1:160 centromere sufficient enough to diagnose 4 crest/scleroderma or additional tests needed?

A member asked:

Tested positive for 2nd time ana 1:160 centromere on 3/4 n 4/5. tested neg 4 sl-70. what additional test can be done to rule out crest/scleroderma?

A member asked:

What is the best climate for me. i have lupus scleroderma ra fibromyalgia and crest syndrome ?

A member asked:

Ana positive 1:80 homogeneous pattern & 1:160 centromere pattern...additional tests needed or just by centromere pattern crest & scleroderma r present?

A member asked:

Can i have secondary pulmonary hypertension due to crest scleroderma?

A member asked:

Other than crest/scleroderma what other virus/bacteria/disease can cause a positive ana with centromere pattern?

A member asked:

Is crest syndrome with high centromere b antibody considered a rare disorder with rheumatologists having only a few such patients? should i seek out a scleroderma specialty center for regular care?

A member asked:

Ana speckled pattern 1:80 with antigen detected for high sle titer, sjordens, high titers scleroderma, crest and pbc....how worried should i be?

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?