Question 1

how are pancytopenia and myelodysplastic syndrome differentiated?

Accepted Answer

Bone Marrow Biopsy: Pancytopenia is a clinical condition that can be caused by a variety of diseases such as aplastic anemia, myelodysplasia, drug toxicity.  Myelodysplasia is a clinical syndrome that may manifest itself as pancytopenia.  A bone marrow biopsy is the only way to tell what is going on.

Question 2

what are the symptoms of myelodysplastic syndrome?

Accepted Answer

The symptoms of Myelodysplastic syndrome include::   Fatigue, Autoimmune conditions, Bacterial infections, Enlarged liver, Enlarged lymph nodes, Exercise intolerance, Large spleen, Pale skin, Petechiae, Non blanching red or purple spots.

Question 3

what happens to the marrow in myelodysplastic syndrome?

Accepted Answer

Affects production: Myelo=blood.  Dysplasia=abnormal
so what happens is the blood is not getting made normally because the blood cells have what is referred to as dyspoiesis.  So people can present with low red count, low white count and low platelet count.  Treatment either involves transfusions, growth factors or chemotherapy.  Sometimes bone marrow transplant is utilized.

Question 4

what are the marrow features in myelodysplastic syndrome?

Accepted Answer

Myelodysplasia: The typical bone marrow features seen in myelodysplastic syndrome can include a hypercellular marrow (the marrow is too full of cells although in some cases the bone marrow can be more empty (hypocellular).  There is typically disorder growth of cells so that they do not mature normally (dypsoiesis).  Also, many times the chromosomes (cytogenetics) of the bone marrow cells will be abnormal.

Question 5

with myelodysplastic syndrome why does the body stop producing healthy blood?

Accepted Answer

Stem cell problem: Myelodysplastic syndrome is a problem with the bone marrow forming or blood stem cells where the bone marrow does not function normally. There is a disordered production and maturation of the different types of blood cells (white blood cells, red blood cells and platelets) which leads to a decrease in the amount of one or more of these cell types circulating in the blood.

Question 6

what is the treatment for myelodysplastic syndrome?

Accepted Answer

Chemotherapy : There are some chemotherapy drugs that can be used for myelodysplastic syndrome(mds).  Growth factors and transfusions can be used in some cases.  Also, bone marrow or stem cell transplants can be used in some situations.

Question 7

what is myelodysplastic syndrome?

Accepted Answer

Blood disorder: This is a family of diseases that cause bone marrow dysfunction. There are several types that have different prognoses. Some types are precursors to leukemia. They show up a low blood counts usually in older patients.

Question 8

what does this procedure mean? myelodysplastic syndrome

Accepted Answer

Myelodysplastic : Myelodysplastic syndrome (mds) is a category of blood disorder, whereby, the bone marrow is unable to produce normal blood cells (red cells, white blood cells and/or platelets).  Common presentations include one or more of the following:  anemia (low red blood cell count), low white blood cell count and/or thrombocytopenia (low platelet count).

This is a common illness is older persons.  The severity of mds ranges from mild anemia (refractory anemia) to that of advance illness with a pre-leukemia syndrome.  Advanced stage mds may evolve to acute leukemia over time.

Treatment options for mds vary based upon the extent of the disease and age.  For patients with poor risk mds, bone marrow transplant therapy may be a treatment option.  For earlier stage/good risk mds, options may include observation or medications that are designed to allow the bone marrow cells to mature and enter into the blood system.

For more information, visit www.Mds-foundation.Org.

Question 9

what are some of the tests for myelodysplastic syndrome?

Accepted Answer

The tests for Myelodysplastic syndrome include::   Bone marrow biopsy, Complete blood count, Epoetin alfa, HIV test, HLA typing, Reticulocyte count, Vitamin B12 folate (folic acid) blood level, RBC folate (folic acid), Iron and iron binding capacity.

Question 10

would you define low grade myelodysplastic syndrome lesions?

Accepted Answer

MDS: MDS is a group of conditions that involve in abnormal bone marrow changes and lead to inffective blood cell production. Using a comlicated system, MDS can be devided into low-grade (20%). Low-grade MDS does not require chemotherapy and is primarily treated with supportive care.

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Pancytopenia myelodysplastic syndrome

A member asked:

How are pancytopenia and myelodysplastic syndrome differentiated?

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What are the symptoms of myelodysplastic syndrome?

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What happens to the marrow in myelodysplastic syndrome?

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What are the marrow features in myelodysplastic syndrome?

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With myelodysplastic syndrome why does the body stop producing healthy blood?

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What is the treatment for myelodysplastic syndrome?

A member asked:

What is myelodysplastic syndrome?

A member asked:

What does this procedure mean? myelodysplastic syndrome

A member asked:

What are some of the tests for myelodysplastic syndrome?

A member asked:

Would you define low grade myelodysplastic syndrome lesions?

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