Question 1

whats the difference between isosorbide mononitrate vs isosorbide dinitrate?

Accepted Answer

How long they last: The main difference is how long they last.  Most dinitrate products are designed to be taken at least 2 x a day where as most of the mononitrate products once a day.  They both are quite effective at controlling angina when appropriately prescribed.  Some side effects thought a bit less with mono v. Di, but that varies a lot from person to person.

Question 2

should i take isosorbide dinitrate or isosorbide mononitrate?

Accepted Answer

You should take: whichever your health care provider has recommended. Mononitrate has a longer half life and less likely to develop tolerance. Used more commonly in stable angina patients. Ask your health care provider this questions as s/he has your medical history available.

Question 3

does regular isosorbide mononitrate longer lasting than isosorbide dinitrate ? doctor prescribed isosorbide mononitrate 10 mg tab once daily and said its longer than twice daily isosorbide dinitrate ? is that true. ?

Accepted Answer

: Yes, regular isosorbide mononitrate lasts longer than isosorbide dinitrate but with one a day dose you have to use extended release formula. Use REGULAR isosorbide mononitrate for vasospasm prevention then you have to use twice a day, 7 hours apart (instead of 12 hours apart) for minimizing tolerance. Good luck.

Question 4

is isosorbide mononitrate a beta blocker?

Accepted Answer

No: It is a nitrate.  The mechanism of action is different than that of beta blockers.

Question 5

how to diagnose methemoglobinemia? can i develop this from isosorbide mononitrate 20 mg twice daily ?

Accepted Answer

: It can be detected by blood test. No, you are not at risk from this condition when taking isosorbide mononitrate. Take care.

Question 6

i take isosorbide mononitrate er (imdur) 60 mg daily. will i become tolerant to this?! i take it every morning at the same time. 10-11 am?

Accepted Answer

: To avoid tolerance to the medication you have to have about a 12 hour period each day of no medication. With taking every day early in the morning at the same time this allows a drug free time in the day. So you are doing the right thing.

Question 7

isosorbide mononitrate extended-release( imdur) vs quick acting release(by kremers). which one can develop tolerance more. which one prescribed often?

Accepted Answer

Different targets: Either can develop tolerance, long acting a little more likely b/c in system longer. But imdur usually for prolonged venous-dilitation / cardiac perfusion effects and immediate / short formulation more common w/cardiac symptoms. Ask you cardiologist or pharmacist for more specific information.

Question 8

what will happen if i overdose on isosorbide mononitrate?

Accepted Answer

Various: If you are talking about accidentally taking an extra dose, you should expect a headache, and possibly some dizziness from your blood pressure dropping.

Question 9

do you take isosorbide mononitrate 10 mg tab once daily or twice usually ?

Accepted Answer

: Typically you take the first dose as soon as you wake up and the second dose 7 hours later. However, there is variation of dose and how often you take it based on other factors with the patient's health and only the doctor who is prescribed it would know that. Best to discuss with the doctor who prescribed it. Or at least call the pharmacy where the prescription is and find out the correct way.

Question 10

should one increase the isosorbide mononitrate dosage from 10 mg to 30 and?

Accepted Answer

That's ok: Okay to do so but would make sure this is done under physician advice.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

Isosorbide mononitrate vs dinitrate

A member asked:

Whats the difference between isosorbide mononitrate vs isosorbide dinitrate?

A member asked:

Should i take isosorbide dinitrate or isosorbide mononitrate?

A member asked:

Does regular isosorbide mononitrate longer lasting than isosorbide dinitrate ? doctor prescribed isosorbide mononitrate 10 mg tab once daily and said its longer than twice daily isosorbide dinitrate ? is that true. ?

A member asked:

Is isosorbide mononitrate a beta blocker?

A member asked:

How to diagnose methemoglobinemia? can i develop this from isosorbide mononitrate 20 mg twice daily ?

A member asked:

I take isosorbide mononitrate er (imdur) 60 mg daily. will i become tolerant to this?! i take it every morning at the same time. 10-11 am?

A member asked:

Isosorbide mononitrate extended-release( imdur) vs quick acting release(by kremers). which one can develop tolerance more. which one prescribed often?

A member asked:

What will happen if i overdose on isosorbide mononitrate?

A member asked:

Do you take isosorbide mononitrate 10 mg tab once daily or twice usually ?

A member asked:

Should one increase the isosorbide mononitrate dosage from 10 mg to 30 and?

Sponsored Content

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?