Question 1

i have increased iga antibodies, and increased gamma globulin and beta gamma bridging is present. my hepatitis test was negative. i had a low positive ana test. i have iga nephropathy. could i have cirrhosis or something else?

Accepted Answer

: Need other liver tests. Only way to be sure is to have a liver biopsy.

Question 2

i have increased gamma globulins and beta gamma bridging is present on my test. i also have iga nephropathy. my hepatitis test was negative. my ana test was low positive and i have elevated iga. is it likely i have liver cirrhosis or liver disease?

Accepted Answer

: Liver problem is almost always presenting with abnormal liver function tests (enzymes and function) and abnormal liver ultrasound.. Increased serum gamma and beta globulin may be present in liver disease but they are non specific. There is possible relationship between liver disease and IgA nephropathy but not common. IgA is elevated in 50% of patients with IgA nephropathy.

Question 3

increased aldolase,  complement c3/c4 serum, sed rate, c-react. protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Accepted Answer

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist.

Question 4

what is the implication of elevated beta globulin?

Accepted Answer

Nothing by itself: Trivial elevations seen on serum protein electrophoresis reflect normal human variability. Very high transferrin in iron deficiency can raise beta globulin into a spike. Rare IgA monoclonal gammopathies can make a spike here. Otherwise, ignore it.

Question 5

what are the causes for a low total protein level and a low beta globulin level?

Accepted Answer

Ask the doctor: Who ordered your test for a specific reason. Usual causes are infection, inflammation, trauma, malnutrition.

Question 6

what can cause  elevated alkaline phosphatase, beta globulin, tibc, compliment 3 +4 , c-react.protein and low ferritin, mcv, mcg and iron saturation?

Accepted Answer

Low iron: Elevated alk phos is seen with liver and bone disorder. Iron deficiency is suspected, but chronic inflammation may cause most of the lab abnormalities. A hematologist could shed some light on these varied lab abnormalities. Collaboration with a rheumatologist would also be helpful to identify a chronic inflammatory process.

Question 7

what condition presents test results w/: low- rbc, hct, hgb, rdw-cv, neutrophils; high- lymphocytes & sedrate;crp 0.2, rf 12, beta-globulin 1.3, a/g 0.

Accepted Answer

Vague: This is very vague question,  I  need numbers, i need to know the white blood cell count too, lymphoma could cause high lymphocytes.

Question 8

why would an immunologist put me on bactrim (sulfamethoxazole and trimethoprim) for a whole year? should i take probiotic with them? i am 53 years old and have low beta globulin.

Accepted Answer

Bactrim (sulfamethoxazole and trimethoprim) : Bactrim (sulfamethoxazole and trimethoprim) has been used for prevention of urinary tract infections. This approach is being used less these days for several reasons. Treatment for a whole year seems surprising even if your immunoglobulins (gamma globulin) are low. If you have had lots of certain infections maybe he want to prevent more. But the likelihood of getting resistance is high with chronic use of most antibiotics. Bactrim (sulfamethoxazole and trimethoprim) has been used and proven beneficial for prevention of pneumocystis pneumonia. Many immunologists might use antibiotic at the first sign of infection. Ask him/her what the evidence is for this therapy, its pros and cons. Nothing wrong with taking a probiotic with this.

Question 9

doctor ordered spep due to celiac test last year showed iga 525. i did not have celiac. the spep showed elevated beta globulin 2 0.6 and my igm was low 39. she then ordered immunofix no protein. i had radioactive iodine 30mci april 20 concerned?

Accepted Answer

: Radio-iodine treatment would not affect the results of immunofixation. An elevated IgA can be due to number of GI disorders. Your doctor is trying to exclude a monoclonal IgA that can be an indication of a neoplastic process.

Question 10

is beta-2-micro globulin typically elevated in lymphoma patients?

Accepted Answer

A prognositic factor: levels are incorporated into staging system for multiple myeloma.  Higher levels  in 75% cases can correlated with higher tumor burden.

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Doctor answers about:

Increased beta globulin

A member asked:

I have increased iga antibodies, and increased gamma globulin and beta gamma bridging is present. my hepatitis test was negative. i had a low positive ana test. i have iga nephropathy. could i have cirrhosis or something else?

A member asked:

I have increased gamma globulins and beta gamma bridging is present on my test. i also have iga nephropathy. my hepatitis test was negative. my ana test was low positive and i have elevated iga. is it likely i have liver cirrhosis or liver disease?

A member asked:

Increased aldolase, complement c3/c4 serum, sed rate, c-react. protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

A member asked:

What is the implication of elevated beta globulin?

A member asked:

What are the causes for a low total protein level and a low beta globulin level?

A member asked:

What can cause elevated alkaline phosphatase, beta globulin, tibc, compliment 3 +4 , c-react.protein and low ferritin, mcv, mcg and iron saturation?

A member asked:

What condition presents test results w/: low- rbc, hct, hgb, rdw-cv, neutrophils; high- lymphocytes & sedrate;crp 0.2, rf 12, beta-globulin 1.3, a/g 0.

A member asked:

Why would an immunologist put me on bactrim (sulfamethoxazole and trimethoprim) for a whole year? should i take probiotic with them? i am 53 years old and have low beta globulin.

A member asked:

Doctor ordered spep due to celiac test last year showed iga 525. i did not have celiac. the spep showed elevated beta globulin 2 0.6 and my igm was low 39. she then ordered immunofix no protein. i had radioactive iodine 30mci april 20 concerned?

A member asked:

Is beta-2-micro globulin typically elevated in lymphoma patients?

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