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How long until Zoloft takes effect

A 19-year-old male asked:
Dr. Robert Berkowitz
34 years experience Psychiatry
6 months or longer: I'm glad you're feeling better. Zoloft (sertraline) is used to treat depressive and anxiety disorders, so the length of time you will need on it will ... Read More
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A 54-year-old female asked:
Dr. Heidi Fowler
25 years experience Psychiatry
Hope you didn't: start at 150 mg - and worked up to it. It often takes 4 to 6 weeks at an optimal dosage to really start feeling the effects. Occasionally it may start ... Read More
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A 40-year-old member asked:
Dr. Clarence Lyons
20 years experience Family Medicine
Male or woman: Depends. Its half life is long. Average is considered about 24 hours just to get half of it out of your body. It may be 1.5 times longer in women. ... Read More
A 33-year-old member asked:
Dr. John Moranville
36 years experience Psychiatry
5 half lives: Half life is about 28 hours. It takes about 5 half lives to get it all out of your system.
A 33-year-old member asked:
Dr. Kevin Passer
35 years experience Child Psychiatry
Up to six weeks: First of all, there should be no real difference between generic sertraline and brand name zoloft. Also, it depends on what it being prescribed for an ... Read More
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A 42-year-old member asked:
Dr. Alan Ali
Dr. Alan Ali answered
32 years experience Psychiatry
Zoloft (sertraline): Usually 4-6 weeks.
A 34-year-old member asked:
Dr. Mark Reynolds
33 years experience Psychiatry
5 days: 1/2 life is 1 day, 5 half life's to clear. Assuming you are a normal metabolier 5 days would pretty much do it.
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A 50-year-old male asked:
Dr. Dan Fisher
27 years experience Internal Medicine
4 weeks.: Usually best benefit is seen at the 4 week mark.
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A 28-year-old female asked:
Dr. Lynne Weixel
36 years experience Clinical Psychology
Best to work w/ Dr: Discontinuation of these drugs is best done w/ a medical -guided taper but if you can not do that, watch for changes and read advice here (good diet i ... Read More
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A 35-year-old male asked:
Dr. Heidi Fowler
25 years experience Psychiatry
Zoloft (sertraline): It may take 4 to 6 weeks (sometimes as short as 2 weeks) to get the therapeutic effect of an SSRI when on an optimal dose. See that you also take Tra ... Read More
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