Question 1

can epo abuse stop the kidneys from producing their own epo once drug use is ended i've read plenty of research about erythropoietin abuse by athletes, and there is consensus that one of the big risks is polycythemia and the possibility of strokes, hypert

Accepted Answer

Yes, : Yes, once exogenously administered erythropoietin is stopped, assuming that the patient's kidneys are normal (where erythropoietin is primarily made), they should resume making erythropoietin on their own.  Erythropoietin also known as  epo, is a hormone that controls erythropoiesis, or red blood cell production.

Question 2

what stimulates the release of erythropoietin by the kidneys?

Accepted Answer

Hypoxia: This is a very complex process. The simplest answer is: hypoxia (low oxygen tension, anemia) stimulates HIF production (hopoxia-inducible factor) which then stimulates EPO release from the kidney. Another protein called VHL inhibits HIF action on EPO (negative regulator). Mutation of VHL can cause excessive EPO release, resulting in  congenital erythrocytosis (a rare genetic disorder).

Question 3

how effective is erythropoietin for treating chronic kidney disease?

Accepted Answer

Erythropoietin: Erythropoietin is effective in treating CKD-associated anemia but it does not treat or "cure" CKD.

Question 4

labs- erythropoietin 30.3 lactate dehydrogenase 284 transferrin 199 gamma globulin 0.7 spep interpretation consistent with chronic inflammatory pattern and haptoglobin is 225 now to nephrology what could this be! abnormal kidney function at pcp! help?

Accepted Answer

: You should give us the Hb, MCV &amp; MCH if these tests are done for the etiology of anemia. By these numbers, you do not have anemia due to hemolysis, multiple myeloma, less likely iron deficiency but chronic kidney disease-related anemia could not be ruled out. In early stage of CKD, erythropoietin level is still normal and it should be high if you have anemia due to non CKD related diseases.

Question 5

will a person with just "one kidney" need epo?

Accepted Answer

Possibly..: It depends on your residual kidney function, if you are anemic, and if anemia is present without another cause.  If you have decreased kidney function which is determined by your creatinine level (it would be elevated), then you should see a nephrologist who can recommend EPO if necessary.

Question 6

what is epo and when is it recommended for kidney disease?

Accepted Answer

Erythropoeitin: Abbreviated as epo. It is used to help body make new red blood cells i.E boost hemoglobin level and thereby treat anemia. It is generally used when hemoglobin is less than 10 grams/ dl. Also, attention is paid to not exceed hemoglobin of 12 grams.

Question 7

how common is to take epogen procrit (epoetin alfa) for kidney?

Accepted Answer

Depends on stage: In stage 4 and stage 5 (end stage) kidney diseases, Epogen (epoetin alfa) use is common, much more than in lighter stages. Of note, Epogen (epoetin alfa) (procrit) is not taken for kidneys but for anemia caused by kidney disease.

Question 8

can epo secretion be low while kidneys and liver normal. creatinine normal an kidney scan normal. am 70 yrs?

Accepted Answer

Probably not key: I've been following your questions. Especially at age 34, anemia due simply to lack of erythropoietin is extremely uncommon, kidney troubles or no. You need to look for some other cause. Erythropoietin itself is produced irregularly and unless it's way below the reference range (which is set so that several % of healthies fall outside), I'd consider ignoring the result.

Question 9

why pheochromocytoma causes polycythemia vera, it has to do with erythropoietin tumor production?

Accepted Answer

Hypertension: Pheochromocytoma usually causes hypertension, not polycythemia vera.

Question 10

does erythropoietin increase or decrease during anemia?

Accepted Answer

Usually increases: Eryhtropoeitin production is increased as a response to anemia- however in certain conditions this does not happen and levels can remain flat and low.

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Doctor answers about:

Does having only one kidney lower my erythropoietin production

A member asked:

Can epo abuse stop the kidneys from producing their own epo once drug use is ended i've read plenty of research about erythropoietin abuse by athletes, and there is consensus that one of the big risks is polycythemia and the possibility of strokes, hypert

A member asked:

What stimulates the release of erythropoietin by the kidneys?

A member asked:

How effective is erythropoietin for treating chronic kidney disease?

A member asked:

Labs- erythropoietin 30.3 lactate dehydrogenase 284 transferrin 199 gamma globulin 0.7 spep interpretation consistent with chronic inflammatory pattern and haptoglobin is 225 now to nephrology what could this be! abnormal kidney function at pcp! help?

A member asked:

Will a person with just "one kidney" need epo?

A member asked:

What is epo and when is it recommended for kidney disease?

A member asked:

How common is to take epogen procrit (epoetin alfa) for kidney?

A member asked:

Can epo secretion be low while kidneys and liver normal. creatinine normal an kidney scan normal. am 70 yrs?

A member asked:

Why pheochromocytoma causes polycythemia vera, it has to do with erythropoietin tumor production?

A member asked:

Does erythropoietin increase or decrease during anemia?

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