Question 1

can a person with alpha thalassemia marry someone with beta thalassemia safely?

Accepted Answer

Yes: Marriage is no problem. Getting pregnant, however, may not be recommended if they have moderate or severe thalassemia. If they have only "trait", they will be fine if their children only inherit "no trait" or "trait from either mom or dad". If a child inherits "trait" from both mom and dad, the child might have a problem. A geneticist and hematologist can give more details for individual cases.

Question 2

can an alpha thalassemia carrier marry a beta thalassemia carrier?

Accepted Answer

Of course you can: A person can marry anyone they like.  From a thalassemia perspective, and assuming your Alpha thal trait is in cis, your child has a 50/50 chance of being Alpha thal trait vs. Normal and a 50/50 chance of being beta thal trait vs. Normal.  Given there is consideration of inheriting two distinct trait states, it would be prudent to sit with a genetic counselor to understand the implications clearly.

Question 3

is is possible for someone to have both alpha thalassemia and beta thalassemia?

Accepted Answer

Traits, yes: Because the Alpha and beta thalassemia gene mutations are common, it is possible for a baby to inherit one from mom and another from dad. The child could be "trait" in both Alpha and beta, or less likely, be "disease" in one and "trait" in the other. It is hard to imagine being "disease" in both and still survive.

Question 4

is it possible to have both alpha thalassemia and beta thalassemia?

Accepted Answer

Traits, yes: Because the Alpha and beta thalassemia gene mutations are common, it is possible for a baby to inherit one from mom and another from dad. The child could be "trait" in both Alpha and beta, or less likely, be "disease" in one and "trait" in the other. It is hard to imagine being "disease" in both and still survive.

Question 5

what is the difference between alpha and beta thalassemia?  are both the symptoms the same?

Accepted Answer

Similar but differen: Alpha and beta thalassemia are distinct and different disorders since they diminish the production of distinct and different globin polypeptide chains and particularly in the homozygous state that has distinct and different consequences. Alpha and Beta Thal minor are similar
Alpha Thal major is not compatable with life and results in miscarriage. Beta Thal major requires prolonged treatments etc.

Question 6

is beta thalassemia trait distinguish form alpha by the higher amount of red blood cells?

Accepted Answer

: Yes, there is mild microcytic anemia in alpha thalassemia trait.

Question 7

should you go ahead and get the h1n1 vaccine for your child if they have alpha beta thalassemia minor?

Accepted Answer

Yes: The flu vaccine is very important and as long as your child is over 6 months they should receive it.  Children with chronic diseases may receive the inactivated (not live) vaccine, but it is still important to get the vaccine as they are more susceptible to contracting the illness.  Getting vaccinated also helps protect the most vulnerable- babies not old enough to be vaccinated and the elderly.

Question 8

can a person wtih alpha thalassemia trait donate blood?

Accepted Answer

Maybe: A person with Alpha thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more difficult time making hemoglobin (to make new red blood cells), he may not wish to be a blood donor.

Question 9

how can one inherit alpha thalassemia?

Accepted Answer

From Mom and/or Dad: Alpha thalassemia is caused by a mutation in one or more of the 4 genes that code for (holds the dna for) Alpha globulin, which is needed to make hemoglobin for new red blood cells. Mom and/or dad can carry the mutations. A child can inherit a mutation from mom, from dad, or from both mom and dad.

Question 10

what is a 3.7 deletion in alpha thalassemia?

Accepted Answer

: The mutated genes as the cause of alpha thalassemia. If interested, you can read more info from this article for this topic - https://www.nature.com/articles/gim9201117. Take care.

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Can a person with alpha thalassemia marry someone with beta thalassemia safely

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Can a person with alpha thalassemia marry someone with beta thalassemia safely?

A member asked:

Can an alpha thalassemia carrier marry a beta thalassemia carrier?

A member asked:

Is is possible for someone to have both alpha thalassemia and beta thalassemia?

A member asked:

Is it possible to have both alpha thalassemia and beta thalassemia?

A member asked:

What is the difference between alpha and beta thalassemia? are both the symptoms the same?

A member asked:

Is beta thalassemia trait distinguish form alpha by the higher amount of red blood cells?

A member asked:

Should you go ahead and get the h1n1 vaccine for your child if they have alpha beta thalassemia minor?

A member asked:

Can a person wtih alpha thalassemia trait donate blood?

A member asked:

How can one inherit alpha thalassemia?

A member asked:

What is a 3.7 deletion in alpha thalassemia?

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