Question 1

describe microrna gene expression deregulation in human breast cancer?

Accepted Answer

Can't do in 400: The study of micro-rnas is cutting-edge and extremely arcane and you need to go directly to pubmed or one of the other big ways to access the scientific data. If someone is offering a breast cancer treatment to re-regulate your micro-rna's, call your district attorney. Glad you have an inquiring mind and i wish you luck with your project.

Question 2

what happens during the breast cancer gene test?

Accepted Answer

Blood test: It is a blood test to look for the rare brca gene to see if there are increased ridks of breast or ovarian cancer. Is only found in 5% of women for increased breast cancer risk.  See:   http://www.Mayoclinic.Com/health/brca-gene-test/my00322.

Question 3

what's your opinion on the "breast cancer gene test"?

Accepted Answer

BRAC Analysis: As many as 10-15% of breast cancers in the us are believed to be hereditary.  These are linked to mutations of a particular group of genes called the brca genes.  There is a simple blood test to check to see if someone has a brca mutation.  I advise my interested patients to see a genetic counselor to fully understand the ramifications of this test before having it done.

Question 4

can all breast cancer patients carry the brca genes?

Accepted Answer

No!: Many patients with breast cancer have no genetic predisposition or risk for breast cancer.

However, there are several genetic markers which increase the risk of developing breast cancer over a person's lifetime.

Question 5

what are the statistics of the brca/breast cancer gene?

Accepted Answer

Low incidence: Approximately 1 in 40 ashkenazi jewish women have a brca mutation. It also is seen in other isolated populations. A brca1 mutation can be inherited from a mother or father and is associated with up to a 80% lifetime risk of breast cancer and a 40 % risk of ovarian cancer
options include increased surveillance chemo prevention or risk reduction surgery.

Question 6

i'm doing a project and need a gene sequence for breast cancer in chromosome 1.

Accepted Answer

Gene sequencing cos: There are a number of gene sequencing companies that may be able to help you. EG, 23andme, and DNA4life

Question 7

do you think i should get mammograms earlier or be tested for the breast cancer gene?

Accepted Answer

Why?: Do you know of a family risk pattern of breast cancer in a first degree relative (mother, sister, daughter)? Yes you should be having yearly physical examination and mammograms after age 40. Ask your doctor if you should have genetic testing (brca testing).

Question 8

what can my girlfriend do if she is found positive for the breast cancer gene?

Accepted Answer

Difficult: To answer here. Review with her family doctor for referrals. See a medical geneticist. If truly concerned see a medical oncologist to see if there are medications (anti-estrogen hormones) to try. If very concerned or very high risk, sometimes mastectomy and plastic surgery reconstruction is considered.

Question 9

i was wondering is breast cancer a gene or chromosomal disorder?

Accepted Answer

Yes and No: I think you are really asking if breast cancer is hereditary, meaning is it past from a parent  it is possible to inherit a predisposition to breast cancer.  There are a few genes known to cause this like brca 1 ; 2 and tests can be done for them.  On the other hand all breast cancers have genetic abnormalities. These changes however were not inherited but happened in the patient.

Question 10

what do you suggest if my mum died of breast cancer, will my sister have the gene?

Accepted Answer

Not necessarily: Most breast cancers are not caused by an inherited mutation in a gene like BRCA (&quot;the gene&quot;). You should talk to your family doc or GYN and see if they recommend a consultation with a specialist in risk assessment and cancer genetics. Best to you and be safe.

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Doctor answers about:

Breast cancer gene expression

A member asked:

Describe microrna gene expression deregulation in human breast cancer?

A member asked:

What happens during the breast cancer gene test?

A member asked:

What's your opinion on the "breast cancer gene test"?

A member asked:

Can all breast cancer patients carry the brca genes?

A member asked:

What are the statistics of the brca/breast cancer gene?

A member asked:

I'm doing a project and need a gene sequence for breast cancer in chromosome 1.

A member asked:

Do you think i should get mammograms earlier or be tested for the breast cancer gene?

A member asked:

What can my girlfriend do if she is found positive for the breast cancer gene?

A member asked:

I was wondering is breast cancer a gene or chromosomal disorder?

A member asked:

What do you suggest if my mum died of breast cancer, will my sister have the gene?

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