Question 1

result from thyroid fna: indeterminate follicular lesion. is the indeterminate description common? waiting now for genetic test results (2 more weeks)

Accepted Answer

Morphology: Follicular lesions of the thyroid may be difficult to classify based on a limited sample of fna.  Even with biopsy specimens, follicular lesions are hard to separate into benign and malignant tumors.  It is preferable for the pathologist to defer the diagnosis and wait for the genetic test results, if the distinction cannot be made on morphology alone.

Question 2

can genetic testing ever be wrong?

Accepted Answer

Sure: Genetic testing can be wrong due to many possible problems: mixed up specimens from someone else; degraded dna that can't be analyzed; lab errors in procedures; errors in reporting the results.  You should always check on the lab and go over the diagnoses with a physician who knows you and as appropriate with a genetic counselor.  A lot of this testing is highly automated, but can still have error.

Question 3

how much does genetic testing cost?

Accepted Answer

Depends: It really depends.  If your affected family member(s) have already had detailed testing, testing for you can cost just a few hundred dollars, depending on what kind of syndrome.  If you are "fishing" for a diagnosis, this can costs many thousands of dollars.  Generally genetic tests should be done only if there is a specific question that you and your doctor are trying to answer.

Question 4

can you tell me is genetic testing a waste?

Accepted Answer

Depends on situation: Some genetic tests are detailed, specific and allow you to know what to expect from the patient in the future. Chromosome studies, fish probes for diagnostic markers, etc provide information early that allows early detection and treatment of silent problems.Other studies are less specific and only suggest an increased risk for some condition.Value is in the eye of the person seeking information.

Question 5

is genetic testing for adrenoleukodystrophy possible?

Accepted Answer

Yes: Because adrenoleukodystrophy is a genetic condition, there are tests for it. You can find some good information about the disorder, testing and centers that are experts in the disorder at the national organization for rare diseases (nord). Their web site is www.Rarediseases.Org. Disorders are listed alphabetically, along with hospitals/providers that have special expertise in the disorder.

Question 6

how much does genetic testing cost in general (amnio)?

Accepted Answer

Cost of amniocetesis: Cost varies from region to region, but average cost of amniocentesis is about 1500 dollars, if you have insurance and there is a valid indication, it is a covered.

Question 7

is there a genetic testing for sclerodermia? if so, which one?

Accepted Answer

No: There is no known genetic predisposition to scleroderma.

Question 8

can holoprosencephaly be detected early by any genetic testing?

Accepted Answer

Yes: Holoprosencephaly involves abnormal forebrain structure and facial changes ranging from midline cleft lip to single eye (cyclops). Over 30 genes or chromosome regions can be altered to produce holopros, allowing chromosome/gene testing of affected children. Routine and certainly level II ultrasound should pick up holopros in the second trimester of pregnancy, allowing genetic testing by amnio.

Question 9

dx w/ borderline myopathy.  genetic testing next. will it progress or can it stay borderline?

Accepted Answer

Check With NINDS*: Can't answer without a definitive diagnosis.There's a whole laundry list of myopathies and illnesses with a myopathic component.According to the NIH:"The prognosis...varies.Some individuals have a normal life span &amp; little or no disability.For others, however, the disorder may be progressive, severely disabling, life-threatening, or fatal."*
 
* http://www.ninds.nih.gov/disorders/myopathy/myopathy

Question 10

is genetic testing for scn9a readily available through a geneticist? how to locate this biologist?

Accepted Answer

Severe ctl neutrop'?: Do you mean severe congenital neutropenia (scn)? I am not sure what 9a stands for. Thus far we have the following gene mutations known for scn, ela2 (sporadic*); gfi1, csf3r (ad); was (xl); hax1 (ar). Ad stands for autosomal domiant, xl, x linked, and ar autosomal recessive. Please clarify what you mean by 9a.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

Atypical follicular cells genetic testing

A member asked:

Result from thyroid fna: indeterminate follicular lesion. is the indeterminate description common? waiting now for genetic test results (2 more weeks)

A member asked:

Can genetic testing ever be wrong?

A member asked:

How much does genetic testing cost?

A member asked:

Can you tell me is genetic testing a waste?

A member asked:

Is genetic testing for adrenoleukodystrophy possible?

A member asked:

How much does genetic testing cost in general (amnio)?

A member asked:

Is there a genetic testing for sclerodermia? if so, which one?

A member asked:

Can holoprosencephaly be detected early by any genetic testing?

A member asked:

Dx w/ borderline myopathy. genetic testing next. will it progress or can it stay borderline?

A member asked:

Is genetic testing for scn9a readily available through a geneticist? how to locate this biologist?

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?