Question 1

any reason why are most drugs given intravenous and not intra-arterial?

Accepted Answer

Several reasons: Drugs given via an IV route have a chance to diffuse and dilute in the blood stream before hitting the capillaries of the periphery where they may have undesired effects.  In addition the IV route has a first pass through the lungs which may successfully filter out particle that could hurt an peripheral arterial bed.  IVs are also safer and more common.

Question 2

main concern is marfans. has had a main arterial valve replacement. metal. takes all the usual drugs for that. now has developed fluid on lungs. treat?

Accepted Answer

Fluid on lungs: No relation to marfan's but clarification as to where the valve is in place. Could be related to mitral valve leaking, weakness of heart muscle, arrhythmia, leakage of aortic valve, leakage of prosthetic valve. It needs close evaluation

Question 3

can you get coronary artery disease from drugs?

Accepted Answer

Yes: "drugs" is a vague term but if you mean recreational drugs then yes. Marijuana is as bad if not worse than cigarettes. No filter, held for extended time in lungs, and often contains unknown contaminants.So if smoking is a known risk factor....Cocaine tends to cause intense coronary artery vasospasm.This can damage the endothelium and allow cholesterol to deposit in the vessels.

Question 4

can statin drugs reduce need for carotid artery surgery?

Accepted Answer

Rumors exist: There is definitely evidence that the use of statins reduces the incidence of strokes and heart attacks. There have been isolated reports of carotid plaque (narrowing) shrinking with the use of statins but this has not been found true for everybody. Most people agree that statins work by "stabilizing" the plaque and preventing it from rupturing and causing a stroke. This is a hotly debated topic.

Question 5

does the drug vincristine cause blood clots in the bowel, grandad had rcvp them had a blood clot in the major artery supplying the bowel?

Accepted Answer

I suspect this was..: True...True and unrelated. Coagulopathy, is not a side effect of vincristine. However, having a cancer (such as lymphoma that i suspect your dad has) can elevate clotting risk all by itself. Prednisone in rcvp can elevate risk of clotting as well. Additionally, as a 67yo man, he could have had pre-existing vascular disease that elevated his risk for clotting in those vessels that supply the gut.

Question 6

what is an arterial spasm?

Accepted Answer

Muscle contraction: Our arteries are lined on the inside with muscle.  When this muscle contracts and stays like that it can narrow the diameter of the artery.

Question 7

how serious is an arterial injury?

Accepted Answer

Could be bad: If you injure artery in the neck, such as carotid or vertebral dissection, could lead to stroke.  If you injure the largest artery, and burst the aorta, it's death.  If you lacerate an artery, bleeding may be intense.  So, varies, and if you experience bright red bleeding, it may well be arterial in origin.

Question 8

what is done for an arterial occlusion?

Accepted Answer

3 Options: 1)  mechanically remove the clot in an interventional procedure
2)  dissolve the clot using "lytic" medications
3)  do nothing and just try to keep more clots from forming with Heparin or a heparin-like compound.

Those are usually the 3 options.  Specific choice depends on dozens of individual factors.

Question 9

how frequently do arterial clots return?

Accepted Answer

Depends: This is very difficult to answer with out more information.  What type of arterial clot are you talking about?

Question 10

what does it mean if your arterial pressure is too high?

Accepted Answer

Hypertension: It means you have high blood pressure.

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Doctor answers about:

Arterial elongation drugs

A member asked:

Any reason why are most drugs given intravenous and not intra-arterial?

A member asked:

Main concern is marfans. has had a main arterial valve replacement. metal. takes all the usual drugs for that. now has developed fluid on lungs. treat?

A member asked:

Can you get coronary artery disease from drugs?

A member asked:

Can statin drugs reduce need for carotid artery surgery?

A member asked:

Does the drug vincristine cause blood clots in the bowel, grandad had rcvp them had a blood clot in the major artery supplying the bowel?

A member asked:

What is an arterial spasm?

A member asked:

How serious is an arterial injury?

A member asked:

What is done for an arterial occlusion?

A member asked:

How frequently do arterial clots return?

A member asked:

What does it mean if your arterial pressure is too high?

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