Question 1

taking 1mg of tenex (guanfacine) every night made me somewhat hypersexual. however, taking 2mg several days ago made me impotent. can someone please explain how alpha-2 agonists cause impotence?

Accepted Answer

Alpha 1&amp;2 receptors: Try one and one half.

It seems that alpha 2 blockade is used in impotence to increase nitric oxide, but it seems you need both alpha 1 and 2 blockade to block vasoconstriction, since alpha 2 also block the release of norepinephrine and that will increase with alpha blockers.

http://www.ncbi.nlm.nih.gov/pubmed/10845761

Question 2

what's better for a nasal congestion? steroids, antihistamines or alpha agonists?

Accepted Answer

Best to treat cause: It's best to treat the cause of the nasal congestion (allergies, sinus infection, etc.) but for symptomatic relief of the congestion i suggest a steroid nasal spray and oral decongestant if needed.  Different steroid nasal sprays may need to be tried to find one that is most effective.

Question 3

i have very severe pcos where nothing has worked so far. i already lost massive weight and saw no improvement. i do not tolerate the pill & other medications do not do much. i am considering gnrh agonists or a hysterectomy. is this a good option?

Accepted Answer

: Only if you do not want to get pregnant.

Question 4

what is a drug that serves as an agonist for the 2 receptor used for?

Accepted Answer

Acetylcholine: It is an agonist for both muscarinic an nicotinic receptors.

Question 5

help me with understanding agonist and antagonist drug actions?

Accepted Answer

Stimulating vs block: Agonists are stimulators of receptors and antagonists are blockers of receptors.

Question 6

how to clean your nervous system of agonists.is there any drug for that?

Accepted Answer

NO IDEA: Sorry I have no idea what this means. One thing that you can consider a taking antioxidants like Omega 3 Fish Oil.

Question 7

can dopamine agonists like add drugs and levadopa cause problems?

Accepted Answer

Yes: All medications can have side effects or complications.  This must be weighed against the risk of not treating. Dopamine agonists can cause insomnia, tolerance, hallucinations and agitation.  Ldopa used for RLS is usually at a low dose with minimal risk but for parkinsons the above complications should be looked for.  Adhd medications have potential for abuse in patients who don't have true adhd.

Question 8

need expert advice on effects of orchidectomy and lhrh agonist drugs on prostate cancer?

Accepted Answer

Lower testosterone: Orchiectomy and lhrh agonist medications are performed to lower the production of testosterone (fuel that promotes prostate cancer growth).  Both will cause a man's testosterone to drop typically lower than 50 (normal >300).  Will slow prostate cancer growth but not "cure" it. Side-effects of castration include hot-flashes, osteoporosis, diabetes/cardiovascular risks, etc.  Discuss with urologist.

Question 9

what happens if a certain poison/drug blocks the receptor site for a particular neurotransmitter, is it considered an agonist or an antagonist?

Accepted Answer

Could be either: We have both excitatory neurotransmitters (such as glutamate, glycine), and many inhibitory neurotransmitters (norepinephrine, acetylcholine, dopamine, serotonin), and some agents can interfere by imbalancing the homeostasis.  However, mechanistically, receptor blockers really cannot be considered in either category.

Question 10

is wellbutrin (bupropion) a dopamine agonist drug?

Accepted Answer

In short, yes.: Wellbutrin (bupropion) is a norepinephrine/dopamine agonist.

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Doctor answers about:

Alpha agonist medication

A member asked:

Taking 1mg of tenex (guanfacine) every night made me somewhat hypersexual. however, taking 2mg several days ago made me impotent. can someone please explain how alpha-2 agonists cause impotence?

A member asked:

What's better for a nasal congestion? steroids, antihistamines or alpha agonists?

A member asked:

I have very severe pcos where nothing has worked so far. i already lost massive weight and saw no improvement. i do not tolerate the pill & other medications do not do much. i am considering gnrh agonists or a hysterectomy. is this a good option?

A member asked:

What is a drug that serves as an agonist for the 2 receptor used for?

A member asked:

Help me with understanding agonist and antagonist drug actions?

A member asked:

How to clean your nervous system of agonists.is there any drug for that?

A member asked:

Can dopamine agonists like add drugs and levadopa cause problems?

A member asked:

Need expert advice on effects of orchidectomy and lhrh agonist drugs on prostate cancer?

A member asked:

What happens if a certain poison/drug blocks the receptor site for a particular neurotransmitter, is it considered an agonist or an antagonist?

A member asked:

Is wellbutrin (bupropion) a dopamine agonist drug?

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