Studies using these systems are ongoing and none to date have confirmed reports of any significant association between most vaccines and severe side effects that would outweigh the benefits of these important and lifesaving agents. No vaccine is 100% safe. Allergic and serious reactions are possible. In 2 cases, the early oral live polio vaccine and the first rotavirus vaccine, problems did occur, and some were serious. It is important to note, however, that even in these cases, the vaccines were withdrawn and the severe events were still far fewer than the number of lives saved. Both of these vaccines have been changed and are now safe.
39 year experience in Internal Medicine
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