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Conditions
Blood disorders
Anemia
Congenital hemolytic anemia
Hereditary spherocytosis

Hereditary spherocytosis

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Hereditary form of a blood disorder, inherited in a dominant fashion such that its presence on one allele/chromosome will be associated with clinical disease. In this blood disorder, the red blood cells are sphere-shaped and less deformable than their normal biconcave counterparts. Hence, these abnormal cells are destroyed during their passage in the spleen (hemolytic anemia).

Dr. Arold Augustin reviewed this

34 years experience

Is a type of:

Congenital hemolytic anemia

How long it usually lasts:

Chronic (lasts years to lifelong)

How common it is:

Common

Symptoms

Fatigue
Pale skin

Medications

Ratings show how effective doctors think these medications are at treating Hereditary spherocytosis
Folic acid
2.5
2 reviews

Other treatments

Supportive care
Blood transfusion

Tests

Bilirubin
Blood smear
Reticulocyte count
Complete blood count
Direct antiglobulin test

Related questions

A 28-year old male asked:

What do I do for hereditary spherocytosis?

2 doctor answers • 3 doctors weighed in

A 41-year old asked:

Can you tell me about hereditary spherocytosis?

1 doctor answer • 1 doctor weighed in

A 29-year old male asked:

What is the definition or description of: hereditary spherocytosis?

1 doctor answer • 4 doctors weighed in

A 35-year old asked:

What are the chances of passing hereditary spherocytosis onto child?

1 doctor answer • 4 doctors weighed in

A 17-year old female asked:

Why do patients with hereditary spherocytosis have fatigabilty?

1 doctor answer • 1 doctor weighed in

A 36-year old asked:

Hi doctors, can you tell me what is hereditary spherocytosis, is it bad?

1 doctor answer • 1 doctor weighed in

A 30-year old asked:

Is fatigue caused by hereditary spherocytosis?

1 doctor answer • 1 doctor weighed in

A member asked:

What determines if hereditary spherocytosis is mild, moderate or major and spleen removal is needed. ?

1 doctor answer • 1 doctor weighed in

A member asked:

My son was just dx with hereditary spherocytosis. I am SO worried about him getting parvovirus and going into Aplastic crisis. What do I watch for??

1 doctor answer • 1 doctor weighed in

A member asked:

My son is 6 and just dx w hereditary spherocytosis. If he gets parovirus will he definitely go into aplastic crisis? How will I know it's parvovirus??

1 doctor answer • 1 doctor weighed in

A member asked:

My five-year-old son is going through a work up to find a hemoglobin disorder. They think it is hereditary spherocytosis. Is this fatal or dangerous??

1 doctor answer • 1 doctor weighed in

A 47-year old female asked about a male:

My son has a blood disorder Hereditary Spherocytosis that increases his bilirubin. Hes not good at aiming at the toilet and sometimes his urine dries orange on the seat. His liver is fine. Could that be bilirubin in urine. Always been like that?

2 doctor answers • 2 doctors weighed in

A member asked:

My 6 yo son was dx with hereditary spherocytosis. I am SO worried about him getting parvovirus and going into Aplastic crisis. What do I watch for??

1 doctor answer • 2 doctors weighed in

A member asked:

Will a child who has mild hereditary spherocytosis automatically go into aplastic Anemia crisis if he gets parvovirus? Will some kids avoid it?

1 doctor answer • 1 doctor weighed in

A member asked:

My 5 yo is being tested for hereditary spherocytosis. Low hgb detected on standard cbc. hgb is 11.5-12.1. No other sx. Will he need spleenectomy??

1 doctor answer • 1 doctor weighed in

A member asked:

20 yrs old male. neutrophil (30%) Basophil (1%) eosinophil (46%) lymphocyte (20%) monocytes (4%) with few bite cells, spherocytes. what's wrong with him? is he allergic and hereditary spherocytosis?

2 doctor answers • 2 doctors weighed in

A member asked about a male:

My son has hereditary spherocytosis. Recently he was dx with an ear infx. Taking augmentin x 8d. He has a few petechiae behind infected ear. Worry?

1 doctor answer • 2 doctors weighed in

A 35-year old female asked:

35 yo female. Spleen 13cm. Normal CBC. Total bili 1.5 direct 0.2. A1C 4.3. Blood smear showed mild spherocytosis. (Paternal uncle=Hered. Spherocytosis). Would HS cause enlarged spleen without anemia?

1 doctor answer • 2 doctors weighed in

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Is parkinsons disease hereditary?

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Both my mom and aunt have been diagnosed with lupus, should I get checked for it as well? Since I know its hereditary

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My dad;s cousin had non hodgkins lymphoma when she was in her 40's -- is it hereditary?

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Is height a hereditary factor?

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Names of physical or mental non hereditary deaseses?

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